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Selank
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Heptapeptide Research

Selank

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Shipped in POWDER FORM and requires reconstitution using our reconstitution solution.

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99.205% · COA Verified · Lot 129954-34-3 · Freedom Diagnostics
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Research Overview

Selank is a synthetic heptapeptide analog of the endogenous immunopeptide tuftsin (Thr-Lys-Pro-Arg), extended with a Pro-Gly-Pro stabilizing sequence. Developed and studied extensively for anxiolytic, nootropic, and immunomodulatory properties, it demonstrates unusually long plasma stability for a short peptide.

Mechanism of Action

Selank modulates the GABAergic system through allosteric potentiation of GABA-A receptors and influences serotonin, dopamine, and enkephalin metabolism. It upregulates BDNF expression, promotes neuroplasticity, and modulates IL-6 and interferon-gamma production in immune cells. The Pro-Gly-Pro extension blocks prolyl endopeptidase cleavage, producing its exceptional metabolic stability.

Experimental Applications

Research includes anxiety neurochemistry, GABAergic pharmacology, BDNF and neurotrophin biology, cognitive function and memory studies, immunomodulation, anti-depressant mechanism research, neuroprotection, enkephalin system modulation, and nootropic peptide pharmacology.

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How Does Selank Compare?

Neuropeptide Research

PropertySelankThymosin Alpha-1GHK-CuBPC-157
TypeAnxiolytic HeptapeptideThymic Peptide / Immune ModulatorCopper-Binding TripeptidePentadecapeptide
Molecular Weight751.84 g/mol3,108.32 g/mol340.38 g/mol1,419.55 g/mol
Amino Acids728315
CAS Number129954-34-362304-98-749557-75-7137525-51-0
FormulaC₃₃H₅₇N₁₁O₉C₁₂₉H₂₁₅N₃₃O₅₅C₁₄H₂₃CuN₆O₄C₆₂H₉₈N₁₆O₂₂
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Research Use Only. All products sold exclusively for in vitro and qualified laboratory research. Not FDA-approved and not for human or animal consumption.

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