GLP-2TZ

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Shipped in POWDER FORM and requires reconstitution using our reconstitution solution.

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99.912% · COA Verified · Lot 2023788-19-2 · Freedom Diagnostics

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Research Overview

GLP-2TZ is a novel 39-amino acid peptide that acts as a dual agonist at both GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors. Its unique dual-pathway mechanism has made it a leading compound in obesity and type 2 diabetes metabolic research.

Mechanism of Action

GLP-2TZ activates both GIPR and GLP-1R, producing synergistic effects on insulin secretion, glucagon suppression, and gastric emptying. GIPR agonism enhances beta-cell function and promotes adipose tissue remodeling. The compound also activates central nervous system pathways to suppress appetite and food intake. The dual-incretin mechanism produces greater metabolic effects than single-pathway agonism.

Experimental Applications

Research includes dual-incretin receptor pharmacology, comparative metabolic outcomes vs. single-pathway agonists, adipose tissue biology, CNS appetite regulation, beta-cell proliferation studies, and novel mechanisms of cardioprotection.

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How Does GLP-2TZ Compare?

GLP-1 & Metabolic Peptides

Property	GLP-2TZ	GLP-1SG	GLP-3RT	AOD-9604
Type	Dual GIP/GLP-1 Receptor Agonist	GLP-1 Receptor Agonist	Triple GIP/GLP-1/Glucagon Agonist	Modified hGH Fragment (176–191)
Molecular Weight	4,813.45 g/mol	4,113.58 g/mol	4,731.28 g/mol	1,815.08 g/mol
Amino Acids	39	31	39	16
CAS Number	2023788-19-2	910463-68-2	2381089-83-2	221231-10-3
Formula	C₂₂₅H₃₄₈N₄₈O₆₈	C₁₈₇H₂₉₁N₄₅O₅₉	C₂₃₁H₃₄₂N₄₈O₆₈	C₇₈H₁₂₃N₂₃O₂₃S₂
	CURRENT	View Product →	View Product →	View Product →

Research Use Only. All products sold exclusively for in vitro and qualified laboratory research. Not FDA-approved and not for human or animal consumption.