Pentadecapeptide Research
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TB-500 is a synthetic analog of thymosin beta-4, a naturally occurring 43-amino acid peptide found in high concentrations in platelets and wound fluids. It is a potent promoter of tissue healing and regeneration, with demonstrated activity across muscle, tendon, ligament, skin, heart, and eye tissue in preclinical models.
TB-500 sequesters G-actin, promoting actin polymerization and cell migration. It upregulates cell-surface receptors including VEGF and plays a direct role in angiogenesis and vasculogenesis. The compound modulates inflammatory cytokines, reduces fibrosis markers, activates stem and progenitor cell differentiation, and promotes cardiac muscle cell repair after ischemic events.
Research applications include tendon, muscle and ligament repair models, cardiac repair and cardioprotection studies, angiogenesis and vasculogenesis research, stem cell activation, anti-fibrosis studies, ocular surface repair, neuroprotection, and systemic tissue regeneration research.
Healing & Recovery Peptides
| Property | TB-500 | BPC-157 | BPC+TB4 Blend | GHK-Cu |
|---|---|---|---|---|
| Type | Actin-Sequestering Peptide | Pentadecapeptide | Research Blend (BPC-157 + TB-500) | Copper-Binding Tripeptide |
| Molecular Weight | 4,963.44 g/mol | 1,419.55 g/mol | Variable (blend) | 340.38 g/mol |
| Amino Acids | 43 | 15 | — | 3 |
| CAS Number | 77591-33-4 | 137525-51-0 | N/A — Research Blend | 49557-75-7 |
| Formula | C₂₁₂H₃₅₀N₅₆O₇₈S | C₆₂H₉₈N₁₆O₂₂ | Blend | C₁₄H₂₃CuN₆O₄ |
| CURRENT | View Product → | View Product → | View Product → |
Research Use Only. All products sold exclusively for in vitro and qualified laboratory research. Not FDA-approved and not for human or animal consumption.
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